ISO 21253‑2 is the second part of the multi-series on water quality and discusses multi-compound class methods. ISO 21253‑2 specifies the criteria for developing an in-house mass spectrometry-based method for quantitative analysis of multiple subgroups of organic substances in the scope of physical-chemical analysis of water.
ISO 21253‑2 supplements ISO/TS 13530 that provides guidance on the initial characterization of the measurement performances, by providing details to select the test matrix and internal standards and criteria for the analyte and internal standard recoveries.
Note: ISO 21253‑2 is not intended as a substitute for the currently applicable analytical standards dedicated to organic compounds but as a resource bringing additional characterization elements.
ISO 21253‑2 on ‘multi-compound class methods for water quality testing’ is useful for:
ISO 21253‑2 proposes a rating-scale method for analytical protocols dedicated to huge numbers of compounds, making it possible to give the method a reliability score for each compound. When a review of these critical points concludes that the method can reliably quantify the analytes, then the initial characterization of the measurement performances of the method can be started.
ISO 21253‑2 specifies the critical points to be considered when developing a mass spectrometry-based method for the analysis of multiple subgroups of organic substances in water samples. The critical points addressed here involve:
ISO 21253‑2 proposes that quality assurance criteria should be made routine to ensure that performance levels do not degrade over time. ISO 21253‑2 helps you to develop an inhouse method to test water quality using mass spectrometry-based methods.
EN ISO 21253-2
ISO 21253-2