Standard

BS EN 17892:2024

Water quality. Determination of selected per- and polyfluoroalkyl substances in drinking water. Method using liquid chromatography/tandem-mass spectrometry (LC-MS/MS)

Current

•

Published:

30 Jun 2024

1 Scope

This document specifies a method for the determination of the dissolved fraction of selected perfluoroalkyl and polyfluoroalkyl substances (PFAS) in non-filtrated drinking water using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The applicability of the method to other types of water like fresh waters (e.g. ground water, surface water) or treated wastewater can be validated separately for each individual case.

For each target compound both, eventually occurring branched isomers and the respective non-branched isomer, are quantified together. The selected set of substances determined by this method is representative for a wide variety of PFAS. This method has been validated for the analytes specified in Table 1. The list given in this table can be modified depending on the purpose and focus of the method. The lower application range of this method can vary depending on the sensitivity of the equipment used and the matrix of the samples. For many substances to which this document applies a limit of quantification (LOQ) of 1 ng/l can be achieved. Using high volume direct injection as described in part A or SPE as described in part B of the method allows lower LOQs. Analytical limitations can occur with short-chain PFAS or PFAS with more than ten carbon atoms in the carbon chain. Actual LOQs can depend on the blank values realized by individual laboratories as well.

NOTE This document enables the analysis of those 20 PFAS which are listed in point 3 of Part B of Annex III of the EU Drinking Water Directive, EU 2020/2184 [4], for the surveillance of the parametric limit value of 0,10 µg/l for the sum of PFAS.

Furthermore, alternatives and substitutes for these PFAS substances can be analysed using this document as well.

Table 1 — Analytes for which a determination was validated in accordance with this method

Analyte	IUPAC name ^a ⁾	Formula	Abbreviation	CAS-RN ^b ⁾
Perfluoro-n-butanoic acid	2,2,3,3,4,4,4-Heptafluorobutanoic acid	C₄HF₇O₂	PFBA	375–22–4
Perfluoro-n- pentanoic acid	2,2,3,3,4,4,5,5,5-Nonafluoropentanoic acid	C₅HF₉O₂	PFPeA	2706–90–3
Perfluoro-n- hexanoic acid	2,2,3,3,4,4,5,5,6,6,6-Undecafluorohexanoic acid	C₆HF₁₁O₂	PFHxA	307–24–4
Perfluoro-n- heptanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoroheptanoic acid	C₇HF₁₃O₂	PFHpA	375–85–9
Perfluoro-n- octanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Pentadecafluorooctanoic acid	C₈HF₁₅O₂	PFOA	335–67–1
Perfluoro-n- nonanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluorononanoic acid	C₉HF₁₇O₂	PFNA	375–95–1
Perfluoro-n- decanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10, 10,10-Nonadecafluorodecanoic acid	C₁₀HF₁₉O₂	PFDA	335–76–2
Perfluoro-n- undecanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10, 10,11,11,11-Heneicosafluoroundecanoic acid	C₁₁HF₂₁O₂	PFUnDA	2058–94–8
Perfluoro-n- dodecanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-Tricosafluorododecanoic acid	C₁₂HF₂₃O₂	PFDoDA	307–55–1
Perfluoro-n- tridecanoic acid	2,2,3,3,4,4,5,5,6,6,7,7,8,8, 9,9,10,10,11,11,12,12, 13,13,13-Pentacosa-fluorotridecanoic acid	C₁₃HF₂₅O₂	PFTrDA	72629–94–8
Perfluoro-n- butanesulfonic acid	1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonic acid	C₄HF₉O₃S	PFBS	375–73–5
Perfluoro-n- pentanesulfonic acid	1,1,2,2,3,3,4,4,5,5,5-Undecafluoropentane-1-sulfonic acid	C₅HF₁₁O₃S	PFPeS	2706–91–4
Perfluoro-n- hexanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexane-1-sulfonic acid	C₆HF₁₃O₃S	PFHxS	355–46–4
Perfluoro-n- heptanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,7-Pentadecafluoroheptane-1-sulfonic acid	C₇HF₁₅O₃S	PFHpS	375–92–8
Perfluoro-n- octanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluorooctane-1-sulfonic acid	C₈HF₁₇O₃S	PFOS	1763–23–1
Perfluoro-n- nonanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Nonaadecafluorononane-1-sulfonic acid	C₉HF₁₉O₃S	PFNS	68259–12–1
Perfluoro-n- decanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heneicosafluorodecane-1-sulfonic acid	C₁₀HF₂₁O₃S	PFDS	335–77–3
Perfluoro-n-undecanesulfonic acid	1,2,2,3,3,4,4,5,5,6,6,7,7,8,8, 9,9,10,10,11,11,11-Tricosafluoroundecane-1-sulfonic acid	C₁₁HF₂₃O₃S	PFUnDS	749786-16-1
Perfluoro-n-dodecanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-Pentacosafluorododecane-1-sulfonic acid	C₁₂HF₂₅O₃S	PFDoDS	79780-39-5
Perfluoro-n-tridecanesulfonic acid	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,13-Heptacosafluorotridecane-1-sulfonic acid	C₁₃HF₂₇O₃S	PFTrDS	791563-89-8
4:2 Fluorotelomer sulfonic acid	3,3,4,4,5,5,6,6,6-Nonafluorohexane-1-sulfonic acid	C₆H₅F₉O₃S	4:2 FTSA	757124–72–4
6:2 Fluorotelomer sulfonic acid	3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctane-1-sulfonic acid	C₈H₅F₁₃O₃S	6:2 FTSA	27619–97–2
8:2 Fluorotelomer sulfonic acid	3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10, 10-Heptadecafluorodecane-1-sulfonic acid	C₁₀H₅F₁₇O₃S	8:2 FTSA	39108–34–4
Perfluorooctanesulfonamide	1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-octanesulfonamide	C₈H₂F₁₇NO₂S	FOSA	754–91–6
N-ethyl perfluorooctanesulfonamidoacetic acid	2-[Ethyl(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctylsulfonyl) amino]acetic acid	C₁₂H₈F₁₇NO₄S	EtFOSAA	2991–50–6
Hexafluoropropylene oxide dimer acid	2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid	C₆HF₁₁O₃	HFPO-DA	13252–13–6
4,8-Dioxa-3H-perfluorononanoic acid	2,2,3-Trifluoro-3-[1,1, 2,2,3,3-hexafluoro-3-(tri-fluoromethoxy)propoxy] propanoic acid	C₇H₂F₁₂O₄	DONA	919005–14–4
Perfluoro-3-methoxypropanoic acid	2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)pro-panoic acid	C₄HF₇O₃	PFMPA (PF4OPeA)	377–73–1
9-Chlorohexa-decafluoro-3-oxanonane-1-sulfonic acid	2-(6-Chloro-1,1,2,2, 3,3,4,4,5,5,6,6-dodeca-fluorohexoxy)-1,1,2,2-tetrafluoroethanesulfonic acid	C₈HClF₁₆O₄S	9Cl-PF3ONS	73606–19–6

a) IUPAC: International Union of Pure and Applied Chemistry

b) CAS-RN: Chemical Abstract Services Registry Number

Product Details

Descriptors

Chemical water pollutants

Drinking water

Mains (water)

Water pollution

Water testing

Chemical analysis and testing

ICS Codes

13.060.50 Examination of water for chemical substances

Committee

EH/3/2

International relationships

Identical to:

EN 17892

ISBN

978 0 539 22271 5

Publisher

BSI