ISO 13304 discusses radiological protection. ISO 13304‑2 is the second part of ISO 13304 multi-series that discusses minimum criteria for electron paramagnetic resonance (EPR) Ex vivo human tooth enamel dosimetry.
ISO 13304‑2 provides the minimum criteria required for quality assurance and quality control, evaluation of the performance and facilitate the comparison of measurements related to absorbed dose estimation obtained in different laboratories applying ex vivo X-band EPR spectroscopy with human tooth enamel.
ISO 13304‑2 covers the determination of absorbed dose in tooth enamel (hydroxyapatite).
ISO 13304‑2 addresses:
Note: ISO 13304‑2 does not cover the calculation of dose to organs or to the body.
ISO 13304‑2on radiological protection is useful for:
Electron paramagnetic resonance (EPR) has become an important approach for retrospective dosimetry in any situation where dosimetric information is potentially incomplete or unknown for an individual. It is now applied widely for retrospective evaluation of doses that were delivered at considerable times in the past and has received attention for use for triage after an incident in which large numbers of people have potentially been exposed to clinically significant levels of radiation.
ISO 13304‑2 provides you with a guideline to perform the ex vivo measurements of human tooth enamel samples by X-band EPR for dose assessment using documented and validated procedures. The minimum requirements for reconstructing the absorbed dose in enamel, by precisely defining the technical aspects of preparing enamel samples, recording EPR spectra, assessment of radiation induced EPR signal, converting EPR yield to dose and performing proficiency tests, are described.
Retrospective dose assessment using EPR has relevance in radiation effect research, validating radio-epidemiological dosimetry systems, medical management, and medical/legal requirements. A part of the information in ISO 13304‑2 is contained in other international guidelines and scientific publications, primarily in the International Atomic Energy Agency’s (IAEA) technical reports series on “Use of electron paramagnetic resonance dosimetry with tooth enamel for retrospective dose assessment.”
ISO 13304-2