ISO/TR 22019 discusses nanotechnologies. ISO/TR 22019 is an international standard that provides considerations for performing toxicokinetic studies with nanomaterials.
ISO/TR 22019 outlines the backgrounds and principles for toxicokinetic studies relevant to nanomaterials.
ISO/TR 22019 is used to evaluate if a NM behaves differently from a similar NM or bulk material with the same chemical composition e.g. about barrier penetration. As for all studies with NMs, a proper characterization of the NM dispersions or aerosols used in the toxicokinetic studies is essential.
ISO/TR 22019 on considerations for performing toxicokinetic studies with nanomaterials is useful for:
Nanomaterials (NMs) are a family of chemicals that, like any other chemical, can exert a range of toxicities. Toxicokinetic can support the safety evaluation of compounds including NMs by identifying potential target organs, and especially for NMs, the potential for persistence in organs (including cellular uptake and compartmentalization).
ISO/TR 22019 guidelines assist you with risk assessment, factors influencing, analytical challenges, issues relevant for dosing conditions, absorption of nanomaterials, absorption of nanomaterials, and metabolism/degradation for performing toxicokinetic studies with nanomaterials.
ISO/TR 22019 assists you to meet minimum consideration for performing toxicokinetic studies with nanomaterials to ensure safety evaluation of compounds including Nms.ISO/TR 22019