ISO/TS 22692 identifies quality metrics for the detection of DNA variants using next generation sequencing (NGS) technology. It also defines the data types, relationships, optionality, cardinalities and terminology bindings of the data.
ISO/TS 22692 provides a basis for sharing and for the application of “high quality” genomic data and contributes to the realization of the precision medicine and the development of relevant industries.
ISO/TS 22692 is intended to serve as a catalogue of sequencing data elements used to address quality metrics for various clinical, industrial and commercial applications. The exchange of these data allows researchers, commercial entities, and regulatory bodies to assess for the purpose of selective utilization of the data by setting application-specific quality criteria.
NOTE: ISO/TS 22692 is not intended for:
ISO/TS 22692 on DNA sequencing quality control metrics is useful for:
Next Generation Sequencing (NGS) technology has drastically reduced the cost and time for genomic analysis due to its rapid progress. Research institutions, corporations, and government agencies are competitively collecting a large volume of genomic data through multi-national, multi-institutional projects.
However, the quality of available genomic data is less than desirable. ISO/TS 22692 helps you to establish consistent quality control metrics for NGS process which includes sample preparation, library preparation, sequencing and data processing.
ISO/TS 22692 provides you with an example of quality control metrics with informative values. ISO/TS 22692 enables you to share high quality genomic data which is required for reliable detection of mutation for both industrial and clinical applications.
ISO/TS 22692