ISO 19290 discusses cigarettes. ISO 19290 is an international standard that provides methods for the determination of tobacco-specific nitrosamines in mainstream cigarette smoke in cigarettes.
ISO 19290 specifies a method for the quantification of four tobacco specific nitrosamines
(TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed-phase high-performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). Under ISO 19290 the quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
ISO 19290 on the determination of tobacco-specific nitrosamines in mainstream cigarette smoke is useful for:
Liquid Chromatography with tandem mass spectrometry (LC-MS-MS) is a powerful analytical technique that combines the separating power of liquid chromatography with the highly sensitive and selective mass analysis capability of triple quadrupole mass spectrometry.
ISO 19290 provides you with a method of quantification to effectively determine the yield of tobacco-specific nitrosamines in mainstream cigarette smoke.
By adopting ISO 19290 the user can produce reliable and consistent data on the yield of tobacco-specific nitrosamines in mainstream cigarette smoke.
BS ISO 19290:2021 supersedes BS ISO 19290:2016, which is withdrawn. The main changes compared to the previous edition are:
ISO 19290:2021